TIMM17A Gene Summary [Human]
Predicted to contribute to protein transmembrane transporter activity. Predicted to be involved in protein import into mitochondrial matrix. Located in mitochondrial inner membrane and nucleoplasm. Is integral component of mitochondrial inner membrane. Part of TIM23 mitochondrial import inner membrane translocase complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | TIMM17A |
| Official Name | translocase of inner mitochondrial membrane 17A [Source:HGNC Symbol;Acc:HGNC:17315] |
| Ensembl ID | ENSG00000134375 |
| Bio databases IDs | |
| Aliases | translocase of inner mitochondrial membrane 17A |
| Synonyms | Mitochondrial import inner membrane translocase, Mitochondrial protein import protein 2, mTim17a, TIM17, TIM17A, Timm17, translocase of inner mitochondrial membrane 17A |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TIMM17A often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- TIM22
- enzyme binding
- protein binding
- Tim17/Tim22/Tim23/Pmp24 family
- transporter
Pathways
Biological processes and signaling networks where the TIMM17A gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial inner membrane
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TIMM17A gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein targeting to mitochondrion
- protein import into mitochondrial matrix
- intracellular protein transport
Cellular Component
Where in the cell the gene product is active
- mitochondrial inner membrane presequence translocase complex
- mitochondrion
- mitochondrial inner membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein transmembrane transporter activity