C2orf49 Gene Summary [Human]
Predicted to be involved in embryonic morphogenesis. Located in nucleus. Part of tRNA-splicing ligase complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | C2orf49 |
| Official Name | chromosome 2 open reading frame 49 [Source:HGNC Symbol;Acc:HGNC:28772] |
| Ensembl ID | ENSG00000135974 |
| Bio databases IDs | |
| Aliases | chromosome 2 open reading frame 49, ashwin |
| Synonyms | AI597479, asw, C9h2orf49, chromosome 2 open reading frame 49, expressed sequence AI597479, RGD1310553, similar to human chromosome 2 open reading frame 49 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human C2orf49 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Developmental protein
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human C2orf49 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- embryonic morphogenesis
- tRNA splicing, via endonucleolytic cleavage and ligation
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- nucleoplasm
- tRNA-splicing ligase complex
Molecular Function
What the gene product does at the molecular level
- protein binding