SLC41A2 Gene Summary [Human]

Predicted to enable inorganic cation transmembrane transporter activity. Predicted to be involved in magnesium ion transmembrane transport. Predicted to act upstream of or within metal ion transport. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
SLC41A2
Official Name
solute carrier family 41 member 2 [Source:HGNC Symbol;Acc:HGNC:31045]
Ensembl ID
ENSG00000136052
Bio databases IDs NCBI: 84102 Ensembl: ENSG00000136052
Aliases solute carrier family 41 member 2
Synonyms A230035L05Rik, SLC41A1-L1, solute carrier family 41 member 2, solute carrier family 41, member 2
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SLC41A2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • inorganic uptake permease
  • protein binding
  • magnesium ion transporter
  • transporter
  • Divalent cation transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • organismal death
regulated by
  • Immunoglobulin
  • magnesium
  • FGF2
  • monocrotaline
  • TNF
  • AR
  • beta-estradiol
  • forskolin
  • CHUK
  • sirolimus
regulates
  • magnesium
role in cell
  • proliferation
  • apoptosis
  • migration

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human SLC41A2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cobalt ion transport
  • nickel cation transport
  • manganese ion transport
  • magnesium ion transport
  • iron ion transport

Cellular Component

Where in the cell the gene product is active
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • magnesium ion transmembrane transporter activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.