GCOM1 Gene Summary [Human]
This locus represents naturally occurring readthrough transcription between the neighboring MYZAP (myocardial zonula adherens protein) and POLR2M (polymerase (RNA) II (DNA directed) polypeptide M) genes on chromosome 15. Alternative splicing results in multiple readthrough transcript variants. Readthrough variants may encode proteins that share sequence identity with the upstream gene product or with both the upstream and downstream gene products. Some readthrough transcript variants are also expected to be candidates for nonsense-mediated decay (NMD). [provided by RefSeq, Oct 2013]
Details
| Type | Protein Coding |
| Official Symbol | GCOM1 |
| Official Name | GRINL1A complex locus 1 [Source:HGNC Symbol;Acc:HGNC:26424] |
| Ensembl ID | ENSG00000137878 |
| Bio databases IDs | |
| Aliases | GRINL1A complex locus 1, GCOM1, MYZAP-POLR2M combined locus, MYZAP-POLR2M readthrough |
| Synonyms | AA407270, gcom, GCOM1, MYZAP-POLR2M combined locus, GRINL1A, Myozap, MYZAP, MYZAP-POLR2M, POLR2M-GCOM2-GCOM1 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GCOM1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Putative GRINL1B complex locus protein 2
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown