ILDR2 Gene Summary [Human]
Predicted to act upstream of or within several processes, including homeostasis of number of cells within a tissue; insulin secretion; and response to glucose. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | ILDR2 |
| Official Name | immunoglobulin like domain containing receptor 2 [Source:HGNC Symbol;Acc:HGNC:18131] |
| Ensembl ID | ENSG00000143195 |
| Bio databases IDs | |
| Aliases | immunoglobulin like domain containing receptor 2, LISCH-like, angulin-3 |
| Synonyms | 2810478N18Rik, 3110063L10Rik, C1orf32, D1Ertd471e, Dbsm1, dJ782G3.1, immunoglobulin-like domain containing receptor 2, Ll, LOC100048175, LOC103693676, LOC685277, LOC686794 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ILDR2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- intercellular junctions
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ILDR2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- response to glucose stimulus
- insulin secretion
- homeostasis of number of cells within a tissue
- regulation of RNA splicing
- cell differentiation
- negative regulation of T cell activation
- pancreas development
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- nucleus
- tight junction
- occluding junction
- membrane