Ildr2

Involved in negative regulation of T cell activation and regulation of RNA splicing. Acts upstream of or within several processes, including homeostasis of number of cells within a tissue; insulin secretion; and response to glucose. Located in tight junction. Is expressed in embryo; forebrain; medial ganglionic eminence; and retina. Orthologous to human ILDR2 (immunoglobulin like domain containing receptor 2). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ildr2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ildr2 gene, providing context for its role in the cell.