ARMT1 Gene Summary [Human]
Enables S-adenosylmethionine-dependent methyltransferase activity; enzyme binding activity; and protein carboxyl O-methyltransferase activity. Involved in methylation and regulation of response to DNA damage stimulus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ARMT1 |
| Official Name | acidic residue methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:17872] |
| Ensembl ID | ENSG00000146476 |
| Bio databases IDs | |
| Aliases | acidic residue methyltransferase 1, Protein-glutamate O-methyltransferase |
| Synonyms | 1700052N19Rik, acidic residue methyltransferase 1, AW320013, AW536799, C6orf211, RGD1305235 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ARMT1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Damage-control phosphatase ARMT1-like domain
- enzyme binding
- enzyme
- protein binding
- S-adenosylmethionine-dependent methyltransferase
- protein-glutamate O-methyltransferase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ARMT1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- response to DNA damage stimulus
- methylation
Molecular Function
What the gene product does at the molecular level
- fructose 6-phosphate aldolase activity
- protein binding
- metal ion binding
- phosphatase activity
- protein-glutamate O-methyltransferase activity
- protein carboxyl O-methyltransferase activity
- S-adenosylmethionine-dependent methyltransferase activity
- enzyme binding