PXDNL Gene Summary [Human]
Predicted to enable heme binding activity and peroxidase activity. Predicted to be involved in hydrogen peroxide catabolic process. Predicted to be located in cytoplasm. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | PXDNL |
| Official Name | peroxidasin like [Source:HGNC Symbol;Acc:HGNC:26359] |
| Ensembl ID | ENSG00000147485 |
| Bio databases IDs | |
| Aliases | peroxidasin like, polysomal ribonuclease 1 homolog (Xenopus) |
| Synonyms | peroxidasin like, PMR1, PRM1, VPO2 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PXDNL often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Leucine-rich repeats, outliers
- Leucine-rich repeats, typical (most populated) subfamily
- immunoglobulin domain
- Immunoglobulin I-set domain
- Leucine rich repeat
- Animal haem peroxidase
- Leucine rich repeat C-terminal domain
- enzyme
- Animal heme peroxidases and related proteins
- heme binding
- Leucine Rich repeats (2 copies)
- von Willebrand factor type C domain
- peroxidase
- Immunoglobulin like
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PXDNL gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- response to oxidative stress
- hydrogen peroxide catabolic process
Cellular Component
Where in the cell the gene product is active
- extracellular space
- endoplasmic reticulum
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- peroxidase activity
- metal ion binding
- endonuclease activity
- heme binding