KCTD9 Gene Summary [Human]

Enables cullin family protein binding activity; identical protein binding activity; and protein self-association. Predicted to be involved in intracellular signal transduction; protein homooligomerization; and protein ubiquitination. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
KCTD9
Official Name
potassium channel tetramerization domain containing 9 [Source:HGNC Symbol;Acc:HGNC:22401]
Ensembl ID
ENSG00000104756
Bio databases IDs NCBI: 54793 Ensembl: ENSG00000104756
Aliases potassium channel tetramerization domain containing 9
Synonyms AA675328, AI854539, BTBD27, Kctd9 predicted, potassium channel tetramerisation domain containing 9, potassium channel tetramerization domain containing 9
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human KCTD9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • KHA, dimerization domain of potassium ion channel
  • Broad-Complex, Tramtrack and Bric a brac
  • BTB_POZ
  • Ubl1_cv_Nsp3_N-like
  • BTB/POZ domain
  • protein binding
  • Pentapeptide repeats (9 copies)
  • Pentapeptide repeats (8 copies)
  • identical protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • metastasis
  • organismal death
  • inguinal hernia
  • endometriosis
  • colorectal cancer
  • abdominal aortic aneurysm
role in cell
  • proliferation
  • invasion by
  • migration
  • differentiation
  • maturation
  • JQ1-sensitivity
  • cell proliferation
  • degranulation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human KCTD9 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein homooligomerization
  • intracellular signal transduction
  • protein ubiquitination

Molecular Function

What the gene product does at the molecular level
  • identical protein binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.