UTP23 Gene Summary [Human]
Enables mRNA 3'-UTR binding activity and mRNA 5'-UTR binding activity. Predicted to be involved in rRNA processing. Predicted to act upstream of or within endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Implicated in colorectal adenocarcinoma. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | UTP23 |
| Official Name | UTP23 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:28224] |
| Ensembl ID | ENSG00000147679 |
| Bio databases IDs | |
| Aliases | UTP23 small subunit processome component |
| Synonyms | 1700010I21Rik, C8orf53, D530033C11Rik, RGD1307179, UTP23 small subunit processome component, UTP23, small subunit processome component |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human UTP23 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Fcf1
- mRNA 3' UTR binding
- mRNA 5' UTR binding
- protein binding
- PIN (PilT N terminus) domain: Superfamily
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human UTP23 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Cellular Component
Where in the cell the gene product is active
- small-subunit processome
- nucleolus
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- mRNA 5'-UTR binding
- SSU rRNA binding
- mRNA 3'-UTR binding