Utp23 Gene Summary [Mouse]
Predicted to enable mRNA 3'-UTR binding activity; mRNA 5'-UTR binding activity; and small ribosomal subunit rRNA binding activity. Acts upstream of or within endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma. Orthologous to human UTP23 (UTP23 small subunit processome component). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Utp23 |
| Official Name | UTP23 small subunit processome component [Source:MGI Symbol;Acc:MGI:1925831] |
| Ensembl ID | ENSMUSG00000022313 |
| Bio databases IDs | |
| Aliases | UTP23 small subunit processome component |
| Synonyms | 1700010I21Rik, C8orf53, D530033C11Rik, RGD1307179, UTP23 small subunit processome component, UTP23, small subunit processome component |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Utp23 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Fcf1
- mRNA 3' UTR binding
- mRNA 5' UTR binding
- protein binding
- PIN (PilT N terminus) domain: Superfamily
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Utp23 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Cellular Component
Where in the cell the gene product is active
- small-subunit processome
- nucleolus
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- mRNA 5'-UTR binding
- SSU rRNA binding
- mRNA 3'-UTR binding