ZCCHC7 Gene Summary [Human]

Enables RNA binding activity. Located in cytosol and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
ZCCHC7
Official Name
zinc finger CCHC-type containing 7 [Source:HGNC Symbol;Acc:HGNC:26209]
Ensembl ID
ENSG00000147905
Bio databases IDs NCBI: 84186 Ensembl: ENSG00000147905
Aliases zinc finger CCHC-type containing 7
Synonyms 4930572I07RIK, AIR1, D4Wsu132e, HSPC086, LOC683686, zinc finger, CCHC domain containing 7, zinc finger CCHC-type containing 7
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZCCHC7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Crohn disease
  • cardiovascular disorder
  • neonatal asphyxia
  • schizophrenia
  • major depression
  • HER2 negative hormone receptor negative breast cancer
  • metabolic syndrome X
  • bipolar disorder
  • dementia
  • weight gain
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • cytosol
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human ZCCHC7 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • nuclear mRNA surveillance of mRNA 3'-end processing
  • nuclear polyadenylation-dependent rRNA catabolic process
  • nuclear polyadenylation-dependent snoRNA catabolic process
  • nuclear polyadenylation-dependent CUT catabolic process
  • nuclear polyadenylation-dependent snRNA catabolic process
  • nuclear polyadenylation-dependent tRNA catabolic process

Cellular Component

Where in the cell the gene product is active
  • cytosol
  • nucleolus
  • TRAMP complex

Molecular Function

What the gene product does at the molecular level
  • zinc ion binding
  • protein binding
  • RNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.