MPHOSPH6 Gene Summary [Human]
Predicted to enable RNA binding activity. Involved in maturation of 5.8S rRNA. Located in cytosol; nucleolus; and nucleoplasm. Colocalizes with nuclear exosome (RNase complex). [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | MPHOSPH6 |
| Official Name | M-phase phosphoprotein 6 [Source:HGNC Symbol;Acc:HGNC:7214] |
| Ensembl ID | ENSG00000135698 |
| Bio databases IDs | |
| Aliases | M-phase phosphoprotein 6 |
| Synonyms | 1110001M01Rik, M-phase phosphoprotein 6, MPP, MPP-6 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MPHOSPH6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- M-phase phosphoprotein 6
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- cytosol
- nucleoplasm
- nucleoli
- exosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MPHOSPH6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- maturation of 5.8S rRNA
Cellular Component
Where in the cell the gene product is active
- nuclear exosome (RNase complex)
- nucleus
- cytosol
- nucleolus
- nucleoplasm
- exosome (RNase complex)
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding