EML3 Gene Summary [Human]
Predicted to enable microtubule binding activity. Involved in mitotic metaphase plate congression and regulation of mitotic spindle assembly. Located in several cellular components, including midbody; mitotic spindle microtubule; and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | EML3 |
| Official Name | EMAP like 3 [Source:HGNC Symbol;Acc:HGNC:26666] |
| Ensembl ID | ENSG00000149499 |
| Bio databases IDs | |
| Aliases | EMAP like 3 |
| Synonyms | echinoderm microtubule associated protein like 3, ELP95, EMAP3, EMAP95, EMAP like 3, FLJ35827, LOC100362920, LOC102551660, RGD1311368 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human EML3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- WD40 repeats
- HELP motif
- WD domain, G-beta repeat
- WD40
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- microtubule cytoskeleton
- spindle apparatus
- Nucleus
- midbody
- spindle fibers
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human EML3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- microtubule cytoskeleton organization
- mitotic metaphase plate congression
Cellular Component
Where in the cell the gene product is active
- nucleus
- spindle microtubule
- microtubule cytoskeleton
- mitotic spindle
- cytoplasm
- spindle
- midbody
Molecular Function
What the gene product does at the molecular level
- protein binding
- microtubule binding