SLC22A9 Gene Summary [Human]

Enables anion:anion antiporter activity; short-chain fatty acid transmembrane transporter activity; and sodium-independent organic anion transmembrane transporter activity. Involved in hormone transport; short-chain fatty acid import; and sodium-independent organic anion transport. Located in basolateral plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
SLC22A9
Official Name
solute carrier family 22 member 9 [Source:HGNC Symbol;Acc:HGNC:16261]
Ensembl ID
ENSG00000149742
Bio databases IDs NCBI: 114571 Ensembl: ENSG00000149742
Aliases solute carrier family 22 member 9
Synonyms HOAT4, OAT4, OAT7, solute carrier family 22 member 9, ust3, UST3H
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SLC22A9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • benzoate transport
  • Sugar (and other) transporter
  • short-chain fatty acid uptake transporter
  • Major Facilitator Superfamily
  • sodium-independent organic anion transporter
  • organic anion transporter
  • cation transport protein
  • transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
regulates
  • hormone
  • estrone sulfate
  • bumetanide
  • furosemide

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane
  • basolateral membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human SLC22A9 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • hormone transport
  • sodium-independent organic anion transport
  • short-chain fatty acid import
  • organic anion transport

Cellular Component

Where in the cell the gene product is active
  • basolateral plasma membrane

Molecular Function

What the gene product does at the molecular level
  • short-chain fatty acid uptake transporter activity
  • organic anion transmembrane transporter activity
  • sodium-independent organic anion transmembrane transporter activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.