CHPT1 Gene Summary [Human]
Enables diacylglycerol cholinephosphotransferase activity. Involved in phosphatidylcholine biosynthetic process and platelet activating factor biosynthetic process. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | CHPT1 |
| Official Name | choline phosphotransferase 1 [Source:HGNC Symbol;Acc:HGNC:17852] |
| Ensembl ID | ENSG00000111666 |
| Bio databases IDs | |
| Aliases | choline phosphotransferase 1, phosphatidylcholine synthesizing enzyme |
| Synonyms | choline phosphotransferase 1, CPT, CPT1, LOC101928981, LOC101929005, LOC105369940 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CHPT1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- substituted phosphate group transferase
- diacylglycerol cholinephosphotransferase
- enzyme
- protein binding
- CDP-alcohol phosphatidyltransferase
- CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi Apparatus
- Golgi membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CHPT1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- CDP-choline pathway
- regulation of cell growth
- lipid metabolic process
- platelet activating factor biosynthetic process
- phosphatidylcholine biosynthetic process
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- intracellular membrane-bounded organelle
- membrane
- Golgi apparatus
- Golgi membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding
- diacylglycerol cholinephosphotransferase activity
- diacylglycerol binding