BTBD11 Gene Summary [Human]
Predicted to enable protein heterodimerization activity. Predicted to be involved in SMAD protein signal transduction. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | BTBD11 |
| Official Name | BTB domain containing 11 [Source:HGNC Symbol;Acc:HGNC:23844] |
| Ensembl ID | ENSG00000151136 |
| Bio databases IDs | |
| Aliases | BTB domain containing 11, ankyrin repeat and BTB domain containing 3 |
| Synonyms | 6330404E16RIK, ABTB2B, ankyrin repeat and BTB domain containing 3, BTBD11, FLJ33957 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human BTBD11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- histone fold domain (HFD) superfamily
- transcription regulator
- Ankyrin repeats (many copies)
- Broad-Complex, Tramtrack and Bric a brac
- BTB_POZ
- Ankyrin repeats (3 copies)
- BTB/POZ domain
- protein binding
- BACK (BTB and C-terminal Kelch) domain
- PDZ-domain binding
- Ankyrin repeat
- ankyrin repeats
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- idiopathic scoliosis
- coronary artery disease
- myocardial infarction
- diabetic nephropathy
- COVID-19
- metabolic syndrome X
- tinnitus
- organismal death
- human papilloma virus infection
- oral cancer
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- glutaminergic synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human BTBD11 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- exploration behavior
- protein stabilization
- synaptic transmission, glutamatergic
Cellular Component
Where in the cell the gene product is active
- membrane
Molecular Function
What the gene product does at the molecular level
- protein heterodimerization activity
- PDZ domain binding