TRAPPC8 Gene Summary [Human]

Involved in Golgi organization. Part of TRAPP complex. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
TRAPPC8
Official Name
trafficking protein particle complex 8 [Source:HGNC Symbol;Acc:HGNC:29169]
Ensembl ID
ENSG00000153339
Bio databases IDs NCBI: 22878 Ensembl: ENSG00000153339
Aliases trafficking protein particle complex 8, trafficking protein particle complex subunit 8, general sporulation gene 1 homolog (S. cerevisiae)
Synonyms 5033403J15Rik, D030074E01Rik, GSG1, HsT2706, KIAA1012, LOC102554177, LOC108348212, mKIAA1012, RGD1309102, trafficking protein particle complex 8, trafficking protein particle complex subunit 8, TRS85
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TRAPPC8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • ER-Golgi trafficking TRAPP I complex 85 kDa subunit
  • protein binding
  • transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • gout
  • infection by HIV-1
regulated by
  • myoblasts
regulates
  • collagen
role in cell
  • organization

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol
  • cis Golgi networks

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human TRAPPC8 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • ER to Golgi vesicle-mediated transport
  • Golgi organization
  • COPII vesicle coating

Cellular Component

Where in the cell the gene product is active
  • TRAPP complex
  • cytoplasm
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.