APOOL Gene Summary [Human]
This gene encodes a protein which contains an apolipoprotein O superfamily domain. This domain is found on proteins in circulating lipoprotein complexes. [provided by RefSeq, Sep 2011]
Details
| Type | Protein Coding |
| Official Symbol | APOOL |
| Official Name | apolipoprotein O like [Source:HGNC Symbol;Acc:HGNC:24009] |
| Ensembl ID | ENSG00000155008 |
| Bio databases IDs | |
| Aliases | apolipoprotein O like, mitochondrial contact site and cristae organizing system subunit 27 |
| Synonyms | 6720473G16RIK, 9430083G14RIK, apolipoprotein O-like, CXorf33, E130106L15Rik, FAM121A, Mic27, MICOS27, RGD1549725, UNQ8193 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human APOOL often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Apolipoprotein O
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Mitochondria
- alpha granules
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human APOOL gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cristae formation
- inner mitochondrial membrane organization
Cellular Component
Where in the cell the gene product is active
- platelet alpha granule lumen
- mitochondrial crista junction
- mitochondrion
- extracellular region
- mitochondrial sorting and assembly machinery complex
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- protein binding