AK9 Gene Summary [Human]
The protein encoded by this gene catalyzes the interconversion of nucleosides, possessing both nucleoside monophosphate and diphosphate kinase activities. The encoded protein uses these interconversions to maintain nucleoside homeostasis. [provided by RefSeq, Jul 2016]
Details
| Type | Protein Coding |
| Official Symbol | AK9 |
| Official Name | adenylate kinase 9 [Source:HGNC Symbol;Acc:HGNC:33814] |
| Ensembl ID | ENSG00000155085 |
| Bio databases IDs | |
| Aliases | adenylate kinase 9 |
| Synonyms | adenylate kinase 9, AKD1, AKD2, C6ORF199, C6orf224, dJ70A9.1, FLJ42177, Gm234, Gm7127, RGD1559879, RGD1560386, SPGF89 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human AK9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- nucleoside diphosphate kinase
- nucleoside-phosphate kinase
- NK
- adenylate kinase, isozyme 1 subfamily
- N-terminal helicase domain of the DEAD-box helicase superfamily
- YHS
- P-loop containing Nucleoside Triphosphate Hydrolases
- AAA domain
- ATPases associated with a variety of cellular activities
Pathways
Biological processes and signaling networks where the AK9 gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- microtubule cytoskeleton
- Cytoplasm
- cilia
- cytosol
- nucleoplasm
- nuclear envelope
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human AK9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nucleoside monophosphate phosphorylation
Cellular Component
Where in the cell the gene product is active
- nucleus
- nuclear membrane
- cytoplasm
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- nucleoside phosphate kinase activity
- ATPase activity
- adenylate kinase activity
- ATP binding
- nucleoside diphosphate kinase activity