SNX22 Gene Summary [Human]
The protein encoded by this gene is a sorting nexin that is found in the cytoplasm, where it interacts with membrane-bound phosphatidylinositol 3-phosphate. The encoded protein may play a role in intracellular trafficking. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Dec 2012]
Details
| Type | Retained Intron |
| Official Symbol | SNX22 |
| Official Name | sorting nexin 22 [Source:HGNC Symbol;Acc:HGNC:16315] |
| Ensembl ID | ENSG00000157734 |
| Bio databases IDs | |
| Aliases | sorting nexin 22 |
| Synonyms | Gm1120, sorting nexin 22 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SNX22 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- The Phox Homology domain, a phosphoinositide binding module
- protein binding
- PX domain
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SNX22 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein transport
Cellular Component
Where in the cell the gene product is active
- cytoplasmic vesicle membrane
Molecular Function
What the gene product does at the molecular level
- protein binding