COX6B2 Gene Summary [Human]

Predicted to be involved in oxidative phosphorylation. Located in mitochondrial crista. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
COX6B2
Official Name
cytochrome c oxidase subunit 6B2 [Source:HGNC Symbol;Acc:HGNC:24380]
Ensembl ID
ENSG00000160471
Bio databases IDs NCBI: 125965 Ensembl: ENSG00000160471
Aliases cytochrome c oxidase subunit 6B2, cytochrome c oxidase subunit VIb, testes specific, cancer/testis antigen 59
Synonyms 1700067P11Rik, COXVIB2, CT59, cytochrome c oxidase subunit 6B2
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human COX6B2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Cyt_c_Oxidase_VIb
  • enzyme
  • protein binding

Pathways

Biological processes and signaling networks where the COX6B2 gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-small cell lung cancer
  • small cell lung cancer
  • infection by HIV-1
regulated by
role in cell
  • fragmentation
  • fragmentation in
  • tubulation in
  • tubulation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • mitochondrial inner membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human COX6B2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • oxidative phosphorylation

Cellular Component

Where in the cell the gene product is active
  • respiratory chain complex IV
  • mitochondrial crista
  • mitochondrion

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.