LARP4 Gene Summary [Human]
Enables mRNA 3'-UTR binding activity and poly(A) binding activity. Involved in cytoskeleton organization; positive regulation of translation; and regulation of cell morphogenesis. Located in cytosol. Colocalizes with cytoplasmic stress granule; cytosolic small ribosomal subunit; and polysome. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | LARP4 |
| Official Name | La ribonucleoprotein 4 [Source:HGNC Symbol;Acc:HGNC:24320] |
| Ensembl ID | ENSG00000161813 |
| Bio databases IDs | |
| Aliases | La ribonucleoprotein 4, La-related protein 4 |
| Synonyms | DXErtd793, DXErtd793e, La ribonucleoprotein 4, LOC681258, PP13296 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human LARP4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RNA recognition motif (RRM) superfamily
- La domain
- mRNA 3' UTR binding
- RNA recognition motif
- poly(A) binding protein
- protein binding
- LA motif RNA-binding domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- ribosome
- cytosol
- stress granule
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human LARP4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- posttranscriptional regulation of gene expression
- positive regulation of translation
- cytoskeleton organization
- regulation of cell morphogenesis
- translation
Cellular Component
Where in the cell the gene product is active
- cytoplasmic stress granule
- cytosolic small ribosomal subunit
- membrane
- cytosol
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- poly(A) RNA binding
- mRNA 3'-UTR binding