TMOD4 Gene Summary [Human]
Predicted to enable tropomyosin binding activity. Predicted to be involved in actin filament organization; muscle contraction; and myofibril assembly. Located in striated muscle thin filament. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | TMOD4 |
| Official Name | tropomodulin 4 [Source:HGNC Symbol;Acc:HGNC:11874] |
| Ensembl ID | ENSG00000163157 |
| Bio databases IDs | |
| Aliases | tropomodulin 4, actin-capping protein, skeletal tropomodulin |
| Synonyms | MTMOD, MUSCLE TROPOMYOSIN, SK-TMOD, tropomodulin 4 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TMOD4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Tropomodulin
- tropomyosin binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- myofibrils
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TMOD4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- myofibril assembly
- pointed-end actin filament capping
- muscle contraction
- actin filament organization
Cellular Component
Where in the cell the gene product is active
- striated muscle thin filament
- cytoskeleton
- myofibril
Molecular Function
What the gene product does at the molecular level
- protein binding
- actin binding
- tropomyosin binding