IGFN1 Gene Summary [Human]
Predicted to be involved in homophilic cell adhesion via plasma membrane adhesion molecules; retina layer formation; and synapse assembly. Predicted to be located in Z disc and nucleus. Predicted to be active in synapse. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | IGFN1 |
| Official Name | immunoglobulin like and fibronectin type III domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24607] |
| Ensembl ID | ENSG00000163395 |
| Bio databases IDs | |
| Aliases | immunoglobulin like and fibronectin type III domain containing 1 |
| Synonyms | 9830123M21Rik, DKFZp434B1231, EEF1A2BP1, Igfn1-ps1, immunoglobulin-like and fibronectin type III domain containing 1, RGD1565384 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human IGFN1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Tri-helix bundle domain
- FN3
- immunoglobulin domain
- Immunoglobulin like
- Immunoglobulin I-set domain
- protein binding
- Fibronectin type 3 domain
- Tissue factor
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Z line
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human IGFN1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- Z disc
- nucleus
Molecular Function
What the gene product does at the molecular level
- protein binding