Igfn1 Gene Summary [Mouse]
Acts upstream of or within myoblast differentiation and myoblast fusion. Located in Z disc and nucleus. Is expressed in brain. Orthologous to human IGFN1 (immunoglobulin like and fibronectin type III domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Igfn1 |
| Official Name | immunoglobulin-like and fibronectin type III domain containing 1 [Source:MGI Symbol;Acc:MGI:3045352] |
| Ensembl ID | ENSMUSG00000051985 |
| Bio databases IDs | |
| Aliases | immunoglobulin-like and fibronectin type III domain containing 1 |
| Synonyms | 9830123M21Rik, DKFZp434B1231, EEF1A2BP1, Igfn1-ps1, immunoglobulin-like and fibronectin type III domain containing 1, RGD1565384 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Igfn1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Tri-helix bundle domain
- FN3
- immunoglobulin domain
- Immunoglobulin like
- Immunoglobulin I-set domain
- protein binding
- Fibronectin type 3 domain
- Tissue factor
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Z line
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Igfn1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- Z disc
- nucleus
Molecular Function
What the gene product does at the molecular level
- protein binding