SNRK Gene Summary [Human]
SNRK is a member of the sucrose nonfermenting (SNF)-related kinase family of serine/threonine kinases (Kertesz et al., 2002 [PubMed 12234663]).[supplied by OMIM, Apr 2009]
Details
| Type | Protein Coding |
| Official Symbol | SNRK |
| Official Name | SNF related kinase [Source:HGNC Symbol;Acc:HGNC:30598] |
| Ensembl ID | ENSG00000163788 |
| Bio databases IDs | |
| Aliases | SNF related kinase |
| Synonyms | 2010012F07Rik, E030034B15, HSNFRK, mKIAA0096, Snf1-related kinase, Snfk, SNF related kinase |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SNRK often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- UBA domain-like superfamily
- Serine/Threonine protein kinases, catalytic domain
- protein serine/threonine kinase
- Protein kinase (unclassified specificity)
- Protein Kinases, catalytic domain
- Protein tyrosine and serine/threonine kinase
- ATP binding
- Protein kinase domain
- magnesium ion binding
- Tyrosine kinase, catalytic domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- colorectal cancer
- schizophrenia
- insomnia
- colon neoplasm
- colorectal neoplasia
- sarcoidosis
role in cell
- proliferation
- expression in
- apoptosis
- differentiation
- transcription in
- tumorigenicity
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SNRK gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- myeloid cell differentiation
- protein phosphorylation
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- magnesium ion binding
- ATP binding
- protein serine/threonine kinase activity