TEX264 Gene Summary [Human]
Enables signaling receptor activity. Involved in protein-DNA covalent cross-linking repair. Acts upstream of or within reticulophagy. Located in several cellular components, including autophagosome membrane; endoplasmic reticulum membrane; and replication fork. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | TEX264 |
| Official Name | testis expressed 264, ER-phagy receptor [Source:HGNC Symbol;Acc:HGNC:30247] |
| Ensembl ID | ENSG00000164081 |
| Bio databases IDs | |
| Aliases | testis expressed 264, ER-phagy receptor |
| Synonyms | TEG-264, testis expressed 264, testis expressed 264, ER-phagy receptor, testis expressed gene 264 ER-phagy receptor, ZSIG11 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TEX264 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- signaling receptor activity
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Nucleus
- Endoplasmic Reticulum
- cytosol
- endoplasmic reticulum membrane
- alpha granules
- autophagic vacuoles
- replication fork
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TEX264 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- replication fork
- platelet alpha granule lumen
- nucleus
- cytosol
- endoplasmic reticulum
- extracellular region
- autophagic vacuole membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- signaling receptor activity