RNASE7 Gene Summary [Human]
The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein has broad-spectrum antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | RNASE7 |
| Official Name | ribonuclease A family member 7 [Source:HGNC Symbol;Acc:HGNC:19278] |
| Ensembl ID | ENSG00000165799 |
| Bio databases IDs | |
| Aliases | ribonuclease A family member 7 |
| Synonyms | RAE1, ribonuclease A family member 7 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RNASE7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ribonuclease
- peptidoglycan binding
- enzyme
- protein binding
- RNase_A
- lipopolysaccharide binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RNASE7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- defense response to Gram-negative bacterium
- innate immune response
- antibacterial humoral response
- cytolysis in other organism
- defense response to fungus
- defense response to Gram-positive bacterium
Cellular Component
Where in the cell the gene product is active
- extracellular space
- cytoplasm
- extracellular region
Molecular Function
What the gene product does at the molecular level
- nucleic acid binding
- peptidoglycan binding
- endonuclease activity
- ribonuclease activity
- lipopolysaccharide binding