IFTAP Gene Summary [Human]
This gene encodes a protein that was identified as a cellular interacting partner of non-structural protein 10 of the severe acute respiratory syndrome coronavirus (SARS-CoV). The encoded protein may function as a negative regulator of transcription. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
Details
| Type | Protein Coding |
| Official Symbol | IFTAP |
| Official Name | intraflagellar transport associated protein [Source:HGNC Symbol;Acc:HGNC:25142] |
| Ensembl ID | ENSG00000166352 |
| Bio databases IDs | |
| Aliases | intraflagellar transport associated protein |
| Synonyms | B230118H07Rik, C11orf74, HEPIS, intraflagellar transport associated protein, NWC, RGD1309730 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human IFTAP often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- binding protein
- protein binding
- Intraflagellar transport-associated protein
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- non-motile cilium
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human IFTAP gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- acrosome reaction
- spermatogenesis
Cellular Component
Where in the cell the gene product is active
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding