Iftap Gene Summary [Mouse]
Enables intraciliary transport particle A binding activity. Acts upstream of or within acrosome reaction and spermatogenesis. Located in 9+0 non-motile cilium and cytosol. Is expressed in cerebral cortex ventricular layer and retina. Orthologous to human IFTAP (intraflagellar transport associated protein). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Iftap |
| Official Name | intraflagellar transport associated protein [Source:MGI Symbol;Acc:MGI:1915420] |
| Ensembl ID | ENSMUSG00000027165 |
| Bio databases IDs | |
| Aliases | intraflagellar transport associated protein |
| Synonyms | B230118H07Rik, C11orf74, HEPIS, intraflagellar transport associated protein, NWC, RGD1309730 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Iftap often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- binding protein
- protein binding
- Intraflagellar transport-associated protein
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- non-motile cilium
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Iftap gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- acrosome reaction
- spermatogenesis
Cellular Component
Where in the cell the gene product is active
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding