SNX20 Gene Summary [Human]
SNX20 interacts with the cytoplasmic domain of PSGL1 (SELPLG; MIM 600738) and cycles PSGL1 into endosomes.[supplied by OMIM, Feb 2010]
Details
| Type | Protein Coding |
| Official Symbol | SNX20 |
| Official Name | sorting nexin 20 [Source:HGNC Symbol;Acc:HGNC:30390] |
| Ensembl ID | ENSG00000167208 |
| Bio databases IDs | |
| Aliases | sorting nexin 20, selectin ligand interactor cytoplasmic 1 |
| Synonyms | 9130017C17Rik, RGD1307787, SLIC1, sorting nexin 20 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SNX20 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- phosphatidylinositol-4,5-bisphosphate binding
- The Phox Homology domain, a phosphoinositide binding module
- protein binding
- phosphatidylinositol binding
- PX domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- endosomal membrane
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SNX20 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein transport
Cellular Component
Where in the cell the gene product is active
- early endosome membrane
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- phosphatidylinositol-4,5-bisphosphate binding
- protein binding
- phosphatidylinositol-3-phosphate binding