Snx20 Gene Summary [Rat]

Predicted to enable phosphatidylinositol-3-phosphate binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in protein transport. Predicted to be located in nucleoplasm. Predicted to be active in early endosome membrane. Orthologous to human SNX20 (sorting nexin 20). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Snx20
Official Name
sorting nexin 20 [Source:RGD Symbol;Acc:1307787]
Ensembl ID
ENSRNOG00000014202
Bio databases IDs NCBI: 307742 Ensembl: ENSRNOG00000014202
Aliases sorting nexin 20
Synonyms 9130017C17Rik, RGD1307787, SLIC1, sorting nexin 20
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Snx20 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • phosphatidylinositol-4,5-bisphosphate binding
  • The Phox Homology domain, a phosphoinositide binding module
  • protein binding
  • phosphatidylinositol binding
  • PX domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • Crohn disease
  • inflammatory bowel disease
  • diabetic nephropathy
  • leprosy
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • endosomal membrane
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Snx20 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein transport

Cellular Component

Where in the cell the gene product is active
  • early endosome membrane
  • plasma membrane
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • phosphatidylinositol-4,5-bisphosphate binding
  • protein binding
  • phosphatidylinositol-3-phosphate binding

Gene-Specific Assays for Results You Can Trust

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