PHYHIP Gene Summary [Human]
Enables protein tyrosine kinase binding activity. Involved in protein localization. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | PHYHIP |
| Official Name | phytanoyl-CoA 2-hydroxylase interacting protein [Source:HGNC Symbol;Acc:HGNC:16865] |
| Ensembl ID | ENSG00000168490 |
| Bio databases IDs | |
| Aliases | phytanoyl-CoA 2-hydroxylase interacting protein |
| Synonyms | C630010D02Rik, DYRK1AIP3, DYRK1AP3, KIAA0273, Lnap1ip, LOC102551958, LOC108348161, PAHX-AP, PAHX-AP1, PAHX-AP#1, phytanoyl-CoA 2-hydroxylase interacting protein, phytanoyl-CoA hydroxylase interacting protein |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PHYHIP often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Phytanoyl-CoA hydroxylase-interacting protein C-terminus
- protein kinase binding
- FN3
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- renal clear cell adenocarcinoma
- head and neck squamous cell carcinoma
- epithelial cancer
- urothelial bladder carcinoma
- transitional cell bladder cancer
- head and neck squamous cell cancer
- endometrial adenocarcinoma
- endometrial adenocarcinoma formation
- atherosclerosis
- colon adenocarcinoma
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PHYHIP gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein localization
Cellular Component
Where in the cell the gene product is active
- cytoplasm