Phyhip Gene Summary [Mouse]
Predicted to enable protein tyrosine kinase binding activity. Predicted to be involved in protein localization. Predicted to be active in cytoplasm. Is expressed in several structures, including central nervous system; hemolymphoid system gland; musculoskeletal system; nose; and skin. Orthologous to human PHYHIP (phytanoyl-CoA 2-hydroxylase interacting protein). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Phyhip |
| Official Name | phytanoyl-CoA hydroxylase interacting protein [Source:MGI Symbol;Acc:MGI:1860417] |
| Ensembl ID | ENSMUSG00000003469 |
| Bio databases IDs | |
| Aliases | phytanoyl-CoA hydroxylase interacting protein |
| Synonyms | C630010D02Rik, DYRK1AIP3, DYRK1AP3, KIAA0273, Lnap1ip, LOC102551958, LOC108348161, PAHX-AP, PAHX-AP1, PAHX-AP#1, phytanoyl-CoA 2-hydroxylase interacting protein, phytanoyl-CoA hydroxylase interacting protein |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Phyhip often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Phytanoyl-CoA hydroxylase-interacting protein C-terminus
- protein kinase binding
- FN3
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- renal clear cell adenocarcinoma
- head and neck squamous cell carcinoma
- epithelial cancer
- urothelial bladder carcinoma
- transitional cell bladder cancer
- head and neck squamous cell cancer
- endometrial adenocarcinoma
- endometrial adenocarcinoma formation
- atherosclerosis
- colon adenocarcinoma
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Phyhip gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein localization
Cellular Component
Where in the cell the gene product is active
- cytoplasm