RGPD8 Gene Summary [Human]
Predicted to contribute to GTPase activator activity. Predicted to be involved in NLS-bearing protein import into nucleus. Predicted to be part of nuclear pore. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | RGPD8 |
| Official Name | RANBP2 like and GRIP domain containing 8 [Source:HGNC Symbol;Acc:HGNC:9849] |
| Ensembl ID | ENSG00000169629 |
| Bio databases IDs | |
| Aliases | RANBP2 like and GRIP domain containing 8 |
| Synonyms | RanBP2alpha, RANBP2L1, RANBP2 like and GRIP domain containing 8, RGP8 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RGPD8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Rab binding domain
- golgin-97, RanBP2alpha,Imh1p and p230/golgin-245
- Tetratricopeptide repeats
- GRIP domain
- Pleckstrin homology-like domain
- tetratricopeptide repeat
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RGPD8 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- NLS-bearing substrate import into nucleus
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- nuclear pore
Molecular Function
What the gene product does at the molecular level
- GTPase activator activity
- small GTPase binding