MBD3L1 Gene Summary [Human]
This gene encodes a protein that is related to methyl-CpG-binding proteins but lacks the methyl-CpG binding domain. The protein is localized to discrete areas in the nucleus, and expression appears to be restricted to round spermatids, suggesting that the protein plays a role in the postmeiotic stages of male germ cell development. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | MBD3L1 |
| Official Name | methyl-CpG binding domain protein 3 like 1 [Source:HGNC Symbol;Acc:HGNC:15774] |
| Ensembl ID | ENSG00000170948 |
| Bio databases IDs | |
| Aliases | methyl-CpG binding domain protein 3 like 1 |
| Synonyms | 1700070G05Rik, 1700095H13Rik, MBD3L, methyl-CpG binding domain protein 3-like 1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MBD3L1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- p55-binding region of Methyl-CpG-binding domain proteins MBD
- protein binding
- C-terminal domain of methyl-CpG binding protein 2 and 3
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- heterochromatin
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MBD3L1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of transcription from RNA polymerase II promoter
- methylation-dependent chromatin silencing
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- protein binding
- methyl-CpG binding