COPS9 Gene Summary [Human]

Involved in several processes, including cellular response to UV; cytoplasmic sequestering of protein; and negative regulation of protein neddylation. Located in chromatin; cytoplasm; and nucleoplasm. Colocalizes with COP9 signalosome. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
COPS9
Official Name
COP9 signalosome subunit 9 [Source:HGNC Symbol;Acc:HGNC:21314]
Ensembl ID
ENSG00000172428
Bio databases IDs NCBI: 150678 Ensembl: ENSG00000172428
Aliases COP9 signalosome subunit 9, CSN acidic protein
Synonyms 1110002M09Rik, COP9 signalosome subunit 9, CSNAP, LOC684000, MYEOV2
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human COPS9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • Myeloma-overexpressed-like

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulates
role in cell
  • proliferation
  • neddylation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Cytoplasm
  • nucleoplasm
  • chromatin

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human COPS9 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • positive regulation of cell proliferation
  • cellular response to UV
  • negative regulation of protein neddylation

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • signalosome
  • chromatin
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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