ADGRF3 Gene Summary [Human]

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and cell surface receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Processed Transcript
Official Symbol
ADGRF3
Official Name
adhesion G protein-coupled receptor F3 [Source:HGNC Symbol;Acc:HGNC:18989]
Ensembl ID
ENSG00000173567
Bio databases IDs NCBI: 165082 Ensembl: ENSG00000173567
Aliases adhesion G protein-coupled receptor F3
Synonyms adhesion G protein-coupled receptor F3, Gm1041, GPR113, PGR23
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ADGRF3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • G-protein coupled receptor
  • Hormone receptor domain
  • 7 transmembrane receptor (Secretin family)
  • GPCR proteolysis site, GPS, motif
  • seven-transmembrane G protein-coupled receptor superfamily

Pathways

Biological processes and signaling networks where the ADGRF3 gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human ADGRF3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • G-protein coupled receptor signaling pathway
  • cell surface receptor signaling pathway
  • adenylate cyclase-activating G-protein coupled receptor signaling pathway

Cellular Component

Where in the cell the gene product is active
  • membrane

Molecular Function

What the gene product does at the molecular level
  • G-protein coupled receptor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.