RSRC1 Gene Summary [Human]
This gene encodes a member of the serine and arginine rich-related protein family. The encoded protein is involved in both constitutive and alternative mRNA splicing. This gene may be associated with schizophrenia. A pseudogene of this gene is located on chromosome 9. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]
Details
| Type | Protein Coding |
| Official Symbol | RSRC1 |
| Official Name | arginine and serine rich coiled-coil 1 [Source:HGNC Symbol;Acc:HGNC:24152] |
| Ensembl ID | ENSG00000174891 |
| Bio databases IDs | |
| Aliases | arginine and serine rich coiled-coil 1, splicing factor, arginine/serine-rich 21 |
| Synonyms | 1200013F24Rik, arginine and serine rich coiled-coil 1, arginine/serine-rich coiled-coil 1, BM-011, C80914, MRT70, RGD1304968, SFRS21, SRrp53 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RSRC1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Murine leukemia virus (MLV) integrase (IN) C-terminal domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- gout
- hereditary disorder
- major depression
- breast cancer
- neuroticism
- chronic obstructive pulmonary disease
- autosomal recessive mental retardation type 70
- depressive disorder
- pervasive developmental disorder
- neuroblastoma
role in cell
- splicing by
- alternative splicing by
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RSRC1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nucleocytoplasmic transport
- RNA splicing
- alternative nuclear mRNA splicing, via spliceosome
- response to antibiotic
- nuclear mRNA splicing, via spliceosome
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- nuclear speck
Molecular Function
What the gene product does at the molecular level
- protein binding