ARGLU1 Gene Summary [Human]
Enables cadherin binding activity. Located in cytosol; mitochondrion; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ARGLU1 |
| Official Name | arginine and glutamate rich 1 [Source:HGNC Symbol;Acc:HGNC:25482] |
| Ensembl ID | ENSG00000134884 |
| Bio databases IDs | |
| Aliases | arginine and glutamate rich 1 |
| Synonyms | 9430010O03Rik, arginine and glutamate rich 1, C130008N12, RGD1310061 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ARGLU1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- Arginine and glutamate-rich 1
- transcription co-activator
- protein binding
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- microcephaly
- non-small cell lung cancer
- productive infection by HIV-1
role in cell
- apoptosis
- cell cycle progression
- alternative splicing by
- alternative splicing in
- delocalization
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Mitochondria
- cytosol
- nucleoplasm
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ARGLU1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- cadherin binding