CCDC85B Gene Summary [Human]
Hepatitis delta virus (HDV) is a pathogenic human virus whose RNA genome and replication cycle resemble those of plant viroids. Delta-interacting protein A (DIPA), a cellular gene product, has been found to have homology to hepatitis delta virus antigen (HDAg). DIPA interacts with the viral antigen, HDAg, and can affect HDV replication in vitro. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | CCDC85B |
| Official Name | coiled-coil domain containing 85B [Source:HGNC Symbol;Acc:HGNC:24926] |
| Ensembl ID | ENSG00000175602 |
| Bio databases IDs | |
| Aliases | coiled-coil domain containing 85B, hepatitis delta antigen interacting protein A |
| Synonyms | AI842788, BB115872, coiled-coil domain containing 85B, DIPA, MGC67311, RGD1565319 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CCDC85B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- CCDC85 family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- centrosome
- cell-cell adherens junctions
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CCDC85B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of transcription, DNA-dependent
- negative regulation of cell growth
- cell differentiation
- negative regulation of fat cell differentiation
Cellular Component
Where in the cell the gene product is active
- nucleus
- centrosome
- adherens junction
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- delta-catenin binding
- protein binding