KRT38

KRT38 Gene Summary

The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. [provided by RefSeq, Jul 2008]

Details

Type
Protein Coding
Official Symbol
KRT38
Official Name
keratin 38 [Source:HGNC Symbol;Acc:HGNC:6456]
Ensembl ID
ENSG00000171360
Bio databases IDs NCBI: 8687 Ensembl: ENSG00000171360
Aliases keratin 38
Synonyms
HA8,hHa8,K38,keratin 38,KRTHA8
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • Intermediate filament protein
  • Domain of unknown function (DUF5082)
  • structural molecule

Pathways

Biological processes and signaling networks where the KRT38 gene plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
  • GLRX3
  • LMNA
  • YWHAG
  • ALMS1
  • FAM90A1
  • KIF7
  • TXLNA
  • KLHL38
  • KRT8
  • KRT6A
disease
  • androgenic alopecia
regulated by
  • LINC00941
regulates
role in cell

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the KRT38 gene, providing context for its role in the cell.

BIOLOGICAL PROCESS

Functions and activities the gene product is involved in
  • epithelial cell differentiation
  • intermediate filament organization

CELLULAR COMPONENT

Where in the cell the gene product is active
  • cytoskeleton
  • extracellular vesicular exosome
  • cytosol
  • intermediate filament

MOLECULAR FUNCTION

What the gene product does at the molecular level
  • protein binding
  • structural molecule activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.