The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. [provided by RefSeq, Jul 2008]
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
protein binding
Intermediate filament protein
Domain of unknown function (DUF5082)
structural molecule
Pathways
Biological processes and signaling networks where the KRT38 gene plays a role, providing insight into its function and relevance in health or disease.
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
GLRX3
LMNA
YWHAG
ALMS1
FAM90A1
KIF7
TXLNA
KLHL38
KRT8
KRT6A
disease
androgenic alopecia
regulated by
LINC00941
regulates
role in cell
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
Cytoplasm
cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the KRT38 gene, providing context for its role in the cell.
BIOLOGICAL PROCESS
Functions and activities the gene product is involved in
epithelial cell differentiation
intermediate filament organization
CELLULAR COMPONENT
Where in the cell the gene product is active
cytoskeleton
extracellular vesicular exosome
cytosol
intermediate filament
MOLECULAR FUNCTION
What the gene product does at the molecular level
protein binding
structural molecule activity
Gene-Specific Assays for Results You Can Trust
Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.