TMEM102 Gene Summary [Human]
Involved in regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; response to cytokine; and signal transduction. Acts upstream of or within positive regulation of T cell migration and positive regulation of cell adhesion. Located in cell surface. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | TMEM102 |
| Official Name | transmembrane protein 102 [Source:HGNC Symbol;Acc:HGNC:26722] |
| Ensembl ID | ENSG00000181284 |
| Bio databases IDs | |
| Aliases | transmembrane protein 102, common beta-chain-associated protein |
| Synonyms | 4632403M07Rik, CBAP, D2B, LOC102724073, RGD1559450, Tmem102-ps, transmembrane protein 102 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TMEM102 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TMEM102 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- response to cytokine stimulus
- positive regulation of T cell migration
- regulation of peptidyl-tyrosine phosphorylation
- signal transduction
- apoptotic process
- positive regulation of T cell chemotaxis
- positive regulation of cell adhesion
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- macromolecular complex
- plasma membrane
- cell surface
Molecular Function
What the gene product does at the molecular level
- protein binding