RAB3IL1 Gene Summary [Human]
This gene encodes a guanine nucleotide exchange factor for the ras-related protein Rab3A. The encoded protein binds Rab3a and the inositol hexakisphosphate kinase InsP6K1. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Nov 2012]
Details
| Type | Protein Coding |
| Official Symbol | RAB3IL1 |
| Official Name | RAB3A interacting protein like 1 [Source:HGNC Symbol;Acc:HGNC:9780] |
| Ensembl ID | ENSG00000167994 |
| Bio databases IDs | |
| Aliases | RAB3A interacting protein like 1, guanine nucleotide exchange factor for Rab3A |
| Synonyms | 1200014K04Rik, AI115013, C76746, GRAB, RAB3AIL1, RAB3A interacting protein-like 1, RAB3A interacting protein (rabin3)-like 1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RAB3IL1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Rab11BD_RAB3IP_like
- kinase binding
- guanyl-nucleotide exchange factor
- protein binding
- identical protein binding
- GDP/GTP exchange factor Sec2p
- Domain of unknown function (DUF4200)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RAB3IL1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein transport
- exocytosis
Cellular Component
Where in the cell the gene product is active
- Golgi to plasma membrane transport vesicle
- cytosol
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- guanyl-nucleotide exchange factor activity