TMEM259 Gene Summary [Human]
Predicted to be involved in positive regulation of ERAD pathway and response to endoplasmic reticulum stress. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | TMEM259 |
| Official Name | transmembrane protein 259 [Source:HGNC Symbol;Acc:HGNC:17039] |
| Ensembl ID | ENSG00000182087 |
| Bio databases IDs | |
| Aliases | transmembrane protein 259, membralin, aspecific BCL2 ARE-binding protein 1 |
| Synonyms | AC087114.7gm2, ASBABP1, C19orf6, MBRL, MEMBRALIN, mFLJ00277, ORF61, R32184 3, RGD1311136, transmembrane protein 259 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TMEM259 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Tumour-associated protein
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Endoplasmic Reticulum
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TMEM259 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- response to endoplasmic reticulum stress
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- endoplasmic reticulum