TMEM30B Gene Summary [Human]
Enables aminophospholipid flippase activity. Involved in aminophospholipid transport and positive regulation of protein exit from endoplasmic reticulum. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus; endoplasmic reticulum; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | TMEM30B |
| Official Name | transmembrane protein 30B [Source:HGNC Symbol;Acc:HGNC:27254] |
| Ensembl ID | ENSG00000182107 |
| Bio databases IDs | |
| Aliases | transmembrane protein 30B |
| Synonyms | 9130011B11Rik, CDC50B, transmembrane protein 30B |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TMEM30B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- aminophospholipid transporter
- protein binding
- LEM3 (ligand-effect modulator 3) family / CDC50 family
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Plasma Membrane
- Endoplasmic Reticulum
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TMEM30B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- phospholipid translocation
- aminophospholipid transport
- positive regulation of protein exit from endoplasmic reticulum
Cellular Component
Where in the cell the gene product is active
- Golgi apparatus
- endoplasmic reticulum
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- aminophospholipid transporter activity
- protein binding