Tmem30b Gene Summary [Mouse]
Predicted to enable aminophospholipid flippase activity. Predicted to be involved in aminophospholipid transport; phospholipid translocation; and positive regulation of protein exit from endoplasmic reticulum. Predicted to be part of phospholipid-translocating ATPase complex. Predicted to be active in Golgi apparatus; endoplasmic reticulum; and plasma membrane. Is expressed in several structures, including alimentary system; endocrine gland; forelimb bud; liver; and male reproductive gland or organ. Orthologous to human TMEM30B (transmembrane protein 30B). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tmem30b |
| Official Name | transmembrane protein 30B [Source:MGI Symbol;Acc:MGI:2442082] |
| Ensembl ID | ENSMUSG00000034435 |
| Bio databases IDs | |
| Aliases | transmembrane protein 30B |
| Synonyms | 9130011B11Rik, CDC50B, transmembrane protein 30B |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmem30b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- aminophospholipid transporter
- protein binding
- LEM3 (ligand-effect modulator 3) family / CDC50 family
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Plasma Membrane
- Endoplasmic Reticulum
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmem30b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- phospholipid translocation
- aminophospholipid transport
- positive regulation of protein exit from endoplasmic reticulum
Cellular Component
Where in the cell the gene product is active
- Golgi apparatus
- endoplasmic reticulum
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- aminophospholipid transporter activity
- protein binding