SLC25A18 Gene Summary [Human]
Predicted to enable L-aspartate transmembrane transporter activity and L-glutamate transmembrane transporter activity. Predicted to be involved in L-glutamate transmembrane transport; aspartate transmembrane transport; and malate-aspartate shuttle. Predicted to be located in mitochondrial inner membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | SLC25A18 |
| Official Name | solute carrier family 25 member 18 [Source:HGNC Symbol;Acc:HGNC:10988] |
| Ensembl ID | ENSG00000182902 |
| Bio databases IDs | |
| Aliases | solute carrier family 25 member 18 |
| Synonyms | 1500015I14Rik, AW125787, GC2, solute carrier family 25 member 18, solute carrier family 25 (mitochondrial carrier), member 18 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SLC25A18 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- hydrogen:amino acid symporter
- Mitochondrial carrier protein
- protein binding
- transporter
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SLC25A18 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ion transport
- malate-aspartate shuttle
- L-glutamate transport
- aspartate transport
- L-aspartate transport
Cellular Component
Where in the cell the gene product is active
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- hydrogen:amino acid symporter activity
- protein binding
- L-aspartate transmembrane transporter activity
- L-glutamate transmembrane transporter activity