ARSI Gene Summary [Human]
This gene encodes a protein that belongs to a large family of sulfatases that hydrolyze sulfate esters and sulfamates. Members of this family play a role in several cellular processes, including hormone synthesis, cell signaling in development and degradation of macromolecules. The protein encoded by this gene is thought to be secreted, and to function in extracellular space. [provided by RefSeq, Jul 2016]
Details
| Type | Protein Coding |
| Official Symbol | ARSI |
| Official Name | arylsulfatase family member I [Source:HGNC Symbol;Acc:HGNC:32521] |
| Ensembl ID | ENSG00000183876 |
| Bio databases IDs | |
| Aliases | arylsulfatase family member I |
| Synonyms | arylsulfatase family member I, arylsulfatase family, member I, arylsulfatase i, ASI, RGD1310242, SPG66, SULF5, sulph5 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ARSI often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- alkaline phosphatases and sulfatases
- Sulfatase
- enzyme
- protein binding
- arylsulfatase
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- endoplasmic reticulum lumen
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ARSI gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum lumen
- extracellular region
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding
- arylsulfatase activity